Over a million people in the UK use CBD (cannabidiol) as part of their daily wellbeing routine, from improving sleep to easing stress and supporting recovery. But among all the possible benefits, there’s one reason that consistently tops the list: anxiety relief.
With anxiety disorders becoming increasingly common, many people are seeking natural ways to feel more balanced and in control. For some, CBD has become a popular option. But how exactly can CBD help regulate your mood – and is there any real evidence behind its use?
Why are people turning to CBD for anxiety and mood?
Anxiety is one of the most common mental health conditions in the UK. It's estimated that around 8 million people are living with an anxiety disorder at any one time, with many more experiencing symptoms such as worry, tension or restlessness from time to time.
In response, demand for anxiety support products has surged. While traditional approaches like talking therapy and medication remain vital, many people are also exploring natural options, including CBD, to help ease their symptoms.
CBD oils, gummies and drinks have grown in popularity as convenient and non-intoxicating ways to support emotional balance, without the side effects sometimes associated with pharmaceutical solutions. But does the science back it up?
The evidence: Can CBD help with anxiety?
Over the last decade, there’s been a rapid increase in research into CBD’s potential to support mental wellbeing. Numerous preclinical, clinical and observational studies suggest that CBD may offer anxiolytic (anxiety-reducing) effects.
A 2015 review of 49 studies found strong preclinical evidence for the effectiveness of CBD in managing generalised anxiety disorder, panic disorder, social anxiety disorder, OCD and PTSD, particularly when administered acutely.
Additionally, a clinical study published in 2019 tracked the impact of CBD on sleep and anxiety. After just one month of daily CBD use, anxiety scores dropped in over 79% of participants, with improvements sustained over the study period.
While most of the data comes from short-term or acute dosing, the results are promising, especially when supported by thousands of anecdotal reports from everyday CBD users. Across forums, review sites and social media, many advocates consistently report a reduction in anxiety symptoms and an improved sense of calm after introducing CBD into their routine.
How does CBD work to support mood?
To understand how CBD may influence mood and anxiety, we need to look at how it interacts with the body, in particular the endocannabinoid system (ECS). The ECS is a complex cell-signalling system made up of:
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Endocannabinoids (naturally occurring compounds in the body)
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Cannabinoid receptors (primarily CB1 and CB2, located in the brain, nervous system and immune cells)
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Enzymes that break down these compounds after use
This system plays a role in regulating mood, sleep, appetite, pain perception, immune response and even memory. CBD doesn't bind directly to these receptors in the way THC does, but it is thought to modulate the ECS, supporting balance or “homeostasis” throughout the body.
More specifically:
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CBD is believed to enhance the signalling of serotonin, particularly via the 5-HT1A receptor, which is known to play a key role in anxiety regulation.
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It may also influence GABA activity – the brain’s primary calming neurotransmitter – helping to quiet the noise and promote relaxation.
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Emerging studies suggest CBD could reduce the production of cortisol, the stress hormone and positively influence the dopamine system, which contributes to pleasure and motivation.
In combination, these interactions may help reduce feelings of stress and anxiety while improving focus and emotional stability.
Natural support for a modern world
CBD is not a cure for anxiety, nor is it a substitute for medical treatment in cases of clinical anxiety disorders. But as part of a wider approach to mental wellbeing, including sleep hygiene, movement, therapy and mindful routines, it may offer natural support.
This article is for informational purposes only and does not constitute medical advice. Please consult your healthcare provider before starting any new supplement, especially if you are pregnant, breastfeeding or taking other medications.